DESCRIPTION: The American Society of Addiction Medicine (ASAM) has partnered with nine other medical societies and professional associations representing a wide range of clinical settings and patient populations to provide guidance on evidence-based strategies for tapering benzodiazepine (BZD) medication across a variety of settings.
METHODS: The guideline was developed following modified GRADE methodology and clinical consensus process. The process included a systematic literature review as well as several targeted supplemental searches. The clinical practice guideline was revised based on external stakeholder review.
RECOMMENDATIONS: Key takeaways included the following: Clinicians should engage in ongoing risk-benefit assessment of BZD use/tapering, clinicians should utilize shared decision-making strategies in collaboration with patients, clinicians should not discontinue BZDs abruptly in patients who are likely to be physically dependent and at risk of withdrawal, clinicians should tailor tapering strategies to each patient and adjust tapering based on patient response, and clinicians should offer patients adjunctive psychosocial interventions to support successful tapering.
Specialty Area | Score |
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Family Medicine (FM)/General Practice (GP) | |
General Internal Medicine-Primary Care(US) | |
Hospital Doctor/Hospitalists | |
Internal Medicine |
A useful article to help guide clinical practice related to a relatively common problem.
A very thorough guideline that is a great resource to clinicians, primarily those in primary care practice. The flowcharts and recommendations regarding specific population groups are quite helpful.
A large patient population use benzodiazepines (BZDs) and this multi-institutional clinical guideline will help providers formulate appropriate plans to taper BZDs in patients at risk for adverse effects.
A very important guideline, both for the topic and because it's a joint effort by multiple medical societies. Transparent about evidence gaps and where clinical experience drives recommendations. It's most important lesson is that tapering must be done slowly, with frequent check-ins for signs of withdrawal or recurrence of original symptoms. This offers a useful approach to evaluating risk of withdrawal, but also rightly emphasizes that withdrawal can be hard to predict and can occur even after short periods of low doses. This is an under-appreciated but critical concept. In my experience, the internist says "let's lower your dose to X and return to see me in two weeks," while the experienced psychiatrist or addiction specialist says instead, "let's lower your dose to X, and I want to check in with you in two days to see how you're doing and we'll go from there." These are meaningfully different approaches from which we as internists can learn.